Invention Grant
- Patent Title: TP expression-inhibiting compound and siRNA sequence thereof
- Patent Title (中): TP表达抑制化合物及其siRNA序列
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Application No.: US12484858Application Date: 2009-06-15
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Publication No.: US08110675B2Publication Date: 2012-02-07
- Inventor: Lih-Chyang Chen , Yu-Sun Chang
- Applicant: Lih-Chyang Chen , Yu-Sun Chang
- Applicant Address: TW Tao-Yuan
- Assignee: Chang Gung University
- Current Assignee: Chang Gung University
- Current Assignee Address: TW Tao-Yuan
- Agency: Muncy, Geissler, Olds & Lowe, PLLC
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; A61K31/70 ; C12Q1/68
Abstract:
The present invention discloses a TP expression-inhibiting compound and a TP expression-inhibiting siRNA sequence, wherein a siRNA sequence partially or completely complementary to the sequence of TP is used to inhibit TP expression, whereby is effectively reduced the survival rate of cancer cells in an anoxic environment.
Public/Granted literature
- US20100317839A1 TP EXPRESSION-INHIBITING COMPOUND AND SIRNA SEQUENCE THEREOF Public/Granted day:2010-12-16
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