Invention Grant
- Patent Title: Antibiotic-bound poly(caprolactone) polymer
- Patent Title (中): 抗生素结合聚（己内酯）聚合物
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Application No.: US11746704Application Date: 2007-05-10
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Publication No.: US08110678B2Publication Date: 2012-02-07
- Inventor: Edward Turos , Michelle Leslie
- Applicant: Edward Turos , Michelle Leslie
- Applicant Address: US FL Tampa
- Assignee: University of South Florida
- Current Assignee: University of South Florida
- Current Assignee Address: US FL Tampa
- Agency: Smith & Hopen, P.A.
- Agent Wanhua Zhao
- Main IPC: C07D205/08
- IPC: C07D205/08 ; C07D405/12 ; C07D313/04
Abstract:
This invention is the design and synthesis of a caprolactone monomer which bears a pendant protected carboxyl group. This monomer has been copolymerized with caprolactone in varying ratios. After polymerization, the protecting group can be removed and an antibiotic can be attached as a new pendant group. The bioactivity of the antibiotic-bound poly(caprolactone) polymer is described.
Public/Granted literature
- US20070265243A1 Antibiotic-Bound Poly(Caprolactone) Polymer Public/Granted day:2007-11-15
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