An image sensing device includes a multilayer wiring structure comprising a first wiring layer and a second wiring layer. The second wiring layer comprises a plurality of vertical signal lines extending in the vertical direction among a plurality of photoelectric conversion units of a pixel unit to transfer the signal output by an amplification transistor and a plurality of vertical power supply lines extending in the vertical direction between two pixel units adjacent to each other in the horizontal direction to supply a power supply voltage to the amplification transistor or the reset transistor. The vertical power supply lines supply the power supply voltage to the reset transistor of the adjacent pixel unit on a first side in the horizontal direction and supply the power supply voltage to the amplification transistor of the adjacent pixel unit on a second side in the horizontal direction.