A system and associated methods for orchestrating a collaboration session are disclosed. One method involves orchestrating a collaboration session between a requesting clinician and another clinician where information is exchanged electronically. According to the method, requests for collaboration sessions are received by a computer system from the requesting clinician, with a given request related to a piece of patient-focused clinical data. Each request is analyzed to build a roster of potentially available clinicians for collaboration. A collaboration session is then facilitated between the requesting clinician and one or more of the potentially available clinicians on the roster.