Invention Grant
- Patent Title: IL-17 antagonistic antibodies
- Patent Title (中): IL-17拮抗抗体
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Application No.: US12707934Application Date: 2010-02-18
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Publication No.: US08119131B2Publication Date: 2012-02-21
- Inventor: Franco E Di Padova , Hermann Gram , Hans Hofstetter , Margit Jeschke , Jean-Michel Rondeau , Wim Van Den Berg
- Applicant: Franco E Di Padova , Hermann Gram , Hans Hofstetter , Margit Jeschke , Jean-Michel Rondeau , Wim Van Den Berg
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Leslie Fischer
- Priority: GB0417487.6 20040805
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/46 ; C07K16/24 ; C12P21/08
Abstract:
An IL-17 binding molecule, in particular an antibody to human IL-17, more preferably a human antibody to human IL-17 is provided, wherein the hypervariable regions of the heavy and light chains have amino acid sequences as defined, for use in the treatment of an IL-17 mediated disease or disorder, e.g. rheumatoid arthritis.
Public/Granted literature
- US20100215666A1 IL-17 ANTAGONISTIC ANTIBODIES Public/Granted day:2010-08-26
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