Invention Grant
US08119350B2 Method of surface plasmon resonance (SPR) to detect genomic aberrations in patients with multiple myeloma
失效
表面等离子体共振（SPR）检测多发性骨髓瘤患者基因组畸变的方法
- Patent Title: Method of surface plasmon resonance (SPR) to detect genomic aberrations in patients with multiple myeloma
- Patent Title (中): 表面等离子体共振（SPR）检测多发性骨髓瘤患者基因组畸变的方法
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Application No.: US12441710Application Date: 2007-08-23
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Publication No.: US08119350B2Publication Date: 2012-02-21
- Inventor: Zhong Chen , Ning Liu
- Applicant: Zhong Chen , Ning Liu
- Applicant Address: VG Road Town, Tortola
- Assignee: CMED Technologies Ltd
- Current Assignee: CMED Technologies Ltd
- Current Assignee Address: VG Road Town, Tortola
- Agency: Clayton, Howarth & Cannon, P.C.
- International Application: PCT/US2007/076658 WO 20070823
- International Announcement: WO2008/082710 WO 20080710
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/551 ; G01N33/553
Abstract:
The present invention discloses using SPR technology to detect MM related genomic imbalances in bone marrow samples. An efficient formula to make a mixed SAM that can greatly enhance the immobilization ability of the metal surface in SPR based techniques, which is good for the immobilization of DNA markers used for the identification of MM related genomic imbalances in bone marrow samples is also disclosed.
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