Invention Grant
- Patent Title: Method of screening for compounds that can be used for the treatment of respiratory conditions
- Patent Title (中): 筛选可用于治疗呼吸道疾病的化合物的方法
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Application No.: US12681452Application Date: 2008-10-03
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Publication No.: US08119362B2Publication Date: 2012-02-21
- Inventor: Jacques Barhanin , Christian Gestreau , Richard Warth , Dirk Heitzmann , Jörg Thomas
- Applicant: Jacques Barhanin , Christian Gestreau , Richard Warth , Dirk Heitzmann , Jörg Thomas
- Applicant Address: FR Paris Cedex FR Aix-en-Provence
- Assignee: Centre National de la Recherche Scientifique—Cnrs,Universite Paul Cezanne Marseille III
- Current Assignee: Centre National de la Recherche Scientifique—Cnrs,Universite Paul Cezanne Marseille III
- Current Assignee Address: FR Paris Cedex FR Aix-en-Provence
- Agency: Arent Fox LLP
- Priority: FR0706999 20071005
- International Application: PCT/FR2008/001391 WO 20081003
- International Announcement: WO2009/080910 WO 20090702
- Main IPC: C12Q1/02
- IPC: C12Q1/02 ; C12P21/06 ; C07K1/00
Abstract:
The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein the screening method comprises a step which comprises determining whether the functional activity of a TASK-2 polypeptide in the presence of a test molecule is decreased or eliminated compared with the functional activity of the TASK-2 polypeptide in the absence of the test molecule, the test molecule being considered to be a candidate molecule when it decreases or eliminates the functional activity.
Public/Granted literature
- US20110014642A1 METHOD OF SCREENING FOR COMPOUNDS THAT CAN BE USED FOR THE TREATMENT OF RESPIRATORY CONDITIONS Public/Granted day:2011-01-20
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