Invention Grant
- Patent Title: Method of production of L-amino acids
- Patent Title (中): 生产L-氨基酸的方法
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Application No.: US12466466Application Date: 2009-05-15
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Publication No.: US08119372B2Publication Date: 2012-02-21
- Inventor: Brigitte Bathe , Wilfried Claes
- Applicant: Brigitte Bathe , Wilfried Claes
- Applicant Address: DE Essen
- Assignee: Evonik Degussa GmbH
- Current Assignee: Evonik Degussa GmbH
- Current Assignee Address: DE Essen
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: DE102006032634 20060713
- Main IPC: C12P13/04
- IPC: C12P13/04 ; C12P13/08 ; C12P21/06 ; C12M1/26 ; C12N1/20

Abstract:
An isolated polynucleotide encodes a polypeptide comprising the amino acid sequence of SEQ ID NO: 2, with the L-aspartic acid at position 5 of the amino acid sequence replaced by another proteinogenic amino acid, and possesses citrate synthase activity. In addition, a vector comprises the polynucleotide and a bacterium comprises the vector. An isolated polynucleotide comprises a nucleotide sequence comprising, from position 1 to 39, the nucleotide sequence corresponding to position 1 to 39 of SEQ ID NO: 11, from position 40 to 105, a nucleotide sequence encoding the amino acid sequence of SEQ ID NO: 12, with each proteinogenic amino acid except L-aspartic acid being present at position 5. A method of producing an L-amino acids is also described.
Public/Granted literature
- US20090280542A1 METHOD OF PRODUCTION OF L-AMINO ACIDS Public/Granted day:2009-11-12
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