Invention Grant
- Patent Title: Recombinant microorganisms for increased production of organic acids
- Patent Title (中): 用于增加有机酸生产的重组微生物
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Application No.: US11722579Application Date: 2005-12-16
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Publication No.: US08119377B2Publication Date: 2012-02-21
- Inventor: Jian Yi , Susanne Kleff , Michael V. Guettler
- Applicant: Jian Yi , Susanne Kleff , Michael V. Guettler
- Applicant Address: US MI Lansing
- Assignee: Michigan Biotechnology Institute
- Current Assignee: Michigan Biotechnology Institute
- Current Assignee Address: US MI Lansing
- Agency: Dickinson Wright PLLC
- International Application: PCT/US2005/045714 WO 20051216
- International Announcement: WO2006/083410 WO 20060810
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N15/74

Abstract:
Disclosed are recombinant microorganisms for producing organic acids. The recombinant microorganisms express a polypeptide that has the enzymatic activity of an enzyme that is utilized in the pentose phosphate cycle. The recombinant microorganism may include recombinant Actinobacillus succinogenes that has been transformed to express a Zwischenferment (Zwf) gene. The recombinant microorganisms may be useful in fermentation processes for producing organic acids such as succinic acid and lactic acid. Also disclosed are novel plasmids that are useful for transforming microorganisms to produce recombinant microorganisms that express enzymes such as Zwf.
Public/Granted literature
- US20080305533A1 Recombinant Microorganisms For Increased Production of Organic Acids Public/Granted day:2008-12-11
Information query
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