Invention Grant
- Patent Title: Apoptosis modulator Bcl-B and methods for making and using same
- Patent Title (中): 凋亡调节剂Bcl-B及其制备和使用方法
-
Application No.: US12946722Application Date: 2010-11-15
-
Publication No.: US08119410B2Publication Date: 2012-02-21
- Inventor: John C. Reed , Ning Ke , Adam Godzik
- Applicant: John C. Reed , Ning Ke , Adam Godzik
- Applicant Address: US CA La Jolla
- Assignee: Sanford-Burnham Medical Research Institute
- Current Assignee: Sanford-Burnham Medical Research Institute
- Current Assignee Address: US CA La Jolla
- Agency: Jones Day
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
A novel human member of the Bcl-2 family Bcl-B has been identified, which is closest in amino-acid sequence homology to the Boo (Diva) protein. The Bcl-B protein is widely expressed in adult human tissues. The Bcl-B protein modulates apoptosis. Bcl-B also binds Bcl-2, BCl-XL, and Bax but not Bak. Bcl-B displays a unique pattern of selectivity for binding and regulating the function of other members of the Bcl-2 family.
Public/Granted literature
- US20110190168A1 APOPTOSIS MODULATOR BCL-B AND METHODS FOR MAKING AND USING SAME Public/Granted day:2011-08-04
Information query
IPC分类:
