Invention Grant
- Patent Title: Fused phenyl amido heterocyclic compounds
- Patent Title (中): 稠合苯基酰氨基杂环化合物
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Application No.: US12913059Application Date: 2010-10-27
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Publication No.: US08119624B2Publication Date: 2012-02-21
- Inventor: Hao Bai , Simon Bailey , Dilip Ramakant Bhumralkar , Feng C. Bi , Fengli Guo , Mingying He , Paul Stuart Humphries , Anthony Lai Ling , Jihong Lou , Seiji Nukui , Ru Zhou
- Applicant: Hao Bai , Simon Bailey , Dilip Ramakant Bhumralkar , Feng C. Bi , Fengli Guo , Mingying He , Paul Stuart Humphries , Anthony Lai Ling , Jihong Lou , Seiji Nukui , Ru Zhou
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent John Wichtowski; A. Dean Olson
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/415 ; A61K31/47 ; A61K31/42 ; A61K31/397 ; A61K31/4965 ; A61K31/41 ; C07D215/00 ; C07D401/00 ; C07D413/00 ; C07D405/00 ; C07D403/00 ; C07D231/00

Abstract:
The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein:Ring A is (4-12)-membered heterocyclyl;Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).
Public/Granted literature
- US20110039821A1 Fused Phenyl Amido Heterocyclic Compounds Public/Granted day:2011-02-17
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