Invention Grant
US08119657B2 Enantiomeric compositions of 2-amino-1-(2-isopropylpyrazolo[1,5-α]pyridin-3-yl)propan-1-one and related methods
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2-氨基-1-（2-异丙基吡唑并[1,5-a]吡啶-3-基）丙-1-酮的对映体组合物及相关方法
![Enantiomeric compositions of 2-amino-1-(2-isopropylpyrazolo[1,5-α]pyridin-3-yl)propan-1-one and related methods](/docs/US/2012-02-21/US08119657B2/abs.jpg.600x600.jpg)
- Patent Title: Enantiomeric compositions of 2-amino-1-(2-isopropylpyrazolo[1,5-α]pyridin-3-yl)propan-1-one and related methods
- Patent Title (中): 2-氨基-1-（2-异丙基吡唑并[1,5-a]吡啶-3-基）丙-1-酮的对映体组合物及相关方法
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Application No.: US12820993Application Date: 2010-06-22
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Publication No.: US08119657B2Publication Date: 2012-02-21
- Inventor: Kirk W. Johnson , Matthew I. Gross , Federico C. A. Gaeta
- Applicant: Kirk W. Johnson , Matthew I. Gross , Federico C. A. Gaeta
- Applicant Address: US CA San Diego
- Assignee: MediciNova, Inc.
- Current Assignee: MediciNova, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Sunit Talapatra
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D491/02 ; C07D498/02
![Enantiomeric compositions of 2-amino-1-(2-isopropylpyrazolo[1,5-α]pyridin-3-yl)propan-1-one and related methods](/abs-image/US/2012/02/21/US08119657B2/abs.jpg.150x150.jpg)
Abstract:
Enantiomerically pure (S)-2-amino-1-(2-isopropylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one, (S)-AV1013, is a candidate therapeutic for treating neuropathic pain, addiction behavior and drug withdrawal symptoms. Also described are methods for preparing and using (S)-AV1013, its pharmaceutically acceptable salts as well as pharmaceutically acceptable formulations of the same.
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