Invention Grant
- Patent Title: Carboxylic acid and antidepressant composition containing the same as active ingredient
- Patent Title (中): 含有与活性成分相同的羧酸和抗抑郁药组合物
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Application No.: US12669584Application Date: 2008-07-19
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Publication No.: US08119839B2Publication Date: 2012-02-21
- Inventor: Hiroyuki Yoshimura , Kiyoshi Okihara , Satoshi Kawatake , Hiroko Tani , Tomoki Tatefuji , Ken Hashimoto , Hiromasa Tanaka , Akinori Inoue , Miyako Yanagihara
- Applicant: Hiroyuki Yoshimura , Kiyoshi Okihara , Satoshi Kawatake , Hiroko Tani , Tomoki Tatefuji , Ken Hashimoto , Hiromasa Tanaka , Akinori Inoue , Miyako Yanagihara
- Applicant Address: JP Okayama
- Assignee: Yamada Apiculture Center, Inc.
- Current Assignee: Yamada Apiculture Center, Inc.
- Current Assignee Address: JP Okayama
- Agency: Roylance, Abrams, Berdo & Goodman, L.L.P.
- Priority: JP2007-189606 20070720
- International Application: PCT/JP2008/063073 WO 20080719
- International Announcement: WO2009/014105 WO 20090129
- Main IPC: C07C57/02
- IPC: C07C57/02 ; C07C69/52 ; A01N37/00 ; A01N37/06

Abstract:
The present invention provides a novel compound and antidepressant composition that can be effectively used for improving depressed mood and depressed state, particularly for depressed mood and depressed state in menopausal women. The compound of the present invention is represented by the following formula (1): wherein R1 and R2 are identical or different and represent a hydrogen atom, a hydroxyl group or an acetyloxy group, and n is an integer of 2 to 7, or a pharmaceutically acceptable salt or ester thereof. This compound is used as an active ingredient in the antidepressant composition. Examples of the compound of the invention include (2E)-9,10-dihydroxy-2-decenoic acid, (2Z)-9,10-dihydroxy-2-decenoic acid, (2E)-9-hydroxy-2-decenoic acid, and (2E)-7-acetoxy-2-heptenoic acid.
Public/Granted literature
- US20100184860A1 Novel Carboxylic Acid and Antidepressant Composition Containing the Same as Active Ingredient Public/Granted day:2010-07-22
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