Invention Grant
- Patent Title: Process for synthesis of amino-methyl tetralin derivatives
- Patent Title (中): 合成氨基 - 甲基四氢化萘衍生物的方法
-
Application No.: US12637548Application Date: 2009-12-14
-
Publication No.: US08119842B2Publication Date: 2012-02-21
- Inventor: Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
- Applicant: Kieran Durkin , Lawrence Emerson Fisher , Arthur Meili , Michaelangelo Scalone , Xianqing Shi , Justin Vitale
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLP
- Current Assignee: Roche Palo Alto LLP
- Current Assignee Address: US CA Palo Alto
- Agent Robert C. Hall
- Main IPC: C07C231/18
- IPC: C07C231/18 ; C07C231/12 ; C07C209/50
Abstract:
Methods for producing a compound of formula k1 or k2 by reducing a dihydronapthalene amide compound of formula i with hydrogen gas in the presence of a ruthenium catalyst of formula j1 or j2 Ru(Z)2(L) j1; Ru(E)(E′)(L)(D) j2; wherein m, n, Ar, Y, R1 E, E′, D, Z and L are as defined herein.
Public/Granted literature
- US20100160682A1 PROCESS FOR SYNTHESIS OF AMINO-METHYL TETRALIN DERIVATIVES Public/Granted day:2010-06-24
Information query
