Provided are method and apparatus for eliminating image noise caused by variation between the imaging pixels on an image sensor. Preferably, a uniform light source is provided firstly, and the image sensor records exposure values taken from the source. Method is to sum the exposure values in each channel of each line, and calculate channel's average of sum for each channel and sum for adjacent lines' channels. A channel compensation value is then obtained by subtracting the average from the sum of one channel in one line, and divided by the pixel number in one channel. A compensation average constituted of a first part and a second part for each pixel is further calculated. A pixel compensation value for each pixel is obtained by suitably allotting the two parts. The pixel compensation value is finally recorded in memory and being a reference for future photographing.