Invention Grant
US08124729B2 Splice variants of human G-protein coupled receptor HGPRBMY29 (HGPRMBY29SV2)
有权
人G蛋白偶联受体HGPRBMY29（HGPRBMY29SV2）的剪接变体
- Patent Title: Splice variants of human G-protein coupled receptor HGPRBMY29 (HGPRMBY29SV2)
- Patent Title (中): 人G蛋白偶联受体HGPRBMY29（HGPRBMY29SV2）的剪接变体
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Application No.: US11891240Application Date: 2007-08-09
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Publication No.: US08124729B2Publication Date: 2012-02-28
- Inventor: John N. Feder , Chandra S. Ramanathan , Gabriel A. Mintier , David K. Bol , Donald R. Hawken
- Applicant: John N. Feder , Chandra S. Ramanathan , Gabriel A. Mintier , David K. Bol , Donald R. Hawken
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Stephen C. D'Amico
- Main IPC: C07K1/00
- IPC: C07K1/00 ; C07K14/00 ; C07K17/00 ; C12P21/06 ; C12N1/20 ; C12N15/74
Abstract:
The present invention provides novel polynucleotides encoding HGPRBMY28 and HGPRBMY29 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding splice variants of HGPRBMY29 polypeptides, HGPRBMY29v1 and HGPRBMY29v2. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY28, HGPRBMY29, HGPRBMY29v1, and HGPRBMY29v2 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Public/Granted literature
- US20120010385A1 SPLICE VARIANTS OF HUMAN G-PROTEIN COUPLED RECEPTOR HGPRBMY29 (HGPRMBY29SV2) Public/Granted day:2012-01-12
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