A novel maize variety designated X7K424 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety X7K424 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X7K424 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X7K424, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X7K424. This invention further relates to methods for producing maize varieties derived from maize variety X7K424.