A ferrule arrangement for use in sealing connections to gas chromatography columns includes a generally tubular metal ferrule with an axial bore to receive a fracturable column with a protective coating. The ferrule has a forward part that tapers to a tip region of the ferrule. A generally tubular former has a socket portion to receive the ferrule and further has an internal conical surface that, after such receipt, engages the forward part of the ferrule. A portion is provided on either or both of said ferrule and the former by which the ferrule and former may be directly or indirectly relatively moved together by application of finger force. The taper and the internal conical surface exhibit relative taper angles and the tip region of the ferrule is sufficiently radially thin whereby the application of finger force (i) is adequate to move the ferrule axially into the former to cause the conical surface to engage the tip region of the ferrule and to deform the tip region into sealing engagement with the protective coating of the column, but (ii) does not break the column.