Invention Grant
US08128227B2 Method to detect transmissible spongiform encephalopathies via electroretinogram
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通过视网膜电图检测传染性海绵状脑病的方法
- Patent Title: Method to detect transmissible spongiform encephalopathies via electroretinogram
- Patent Title (中): 通过视网膜电图检测传染性海绵状脑病的方法
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Application No.: US12423046Application Date: 2009-04-14
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Publication No.: US08128227B2Publication Date: 2012-03-06
- Inventor: Justin J. Greenlee , Mary Heather West Greenlee
- Applicant: Justin J. Greenlee , Mary Heather West Greenlee
- Applicant Address: US DC Washington US IA Ames
- Assignee: The United States of America as represented by the Secretary of Agriculture,Iowa State University Research Foundation, Inc.
- Current Assignee: The United States of America as represented by the Secretary of Agriculture,Iowa State University Research Foundation, Inc.
- Current Assignee Address: US DC Washington US IA Ames
- Agent John Fado; Albert Tsui; Lesley Shaw
- Main IPC: A61B3/00
- IPC: A61B3/00

Abstract:
Disclosed is a method for identifying transmissible spongiform encephalopathy in livestock via an electroretinogram, the method comprises producing a biphasic electroretinogram waveform having an a-wave and b-wave from livestock retina in response to photic stimulus, measuring the amplitude of the b-wave, wherein the amplitude is measured from the trough of the a-wave to the peak of the b-wave, measuring the implicit time of the b-wave, wherein the implicit time is measured from onset of photic stimulus to b-wave peak; and comparing said produced waveform to a comparative waveform of livestock known not to have transmissible spongiform encephalopathy, wherein the produced waveform having a decrease b-wave amplitude and increased b-wave implicit time being indicative of livestock having transmissible spongiform encephalopathy.
Public/Granted literature
- US20090257023A1 Method to Detect Transmissible Spongiform Encephalopathies Via Electroretinogram Public/Granted day:2009-10-15
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