Invention Grant
- Patent Title: Renal carcinoma cell line and uses thereof
- Patent Title (中): 肾癌细胞系及其用途
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Application No.: US12083842Application Date: 2006-10-20
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Publication No.: US08128923B2Publication Date: 2012-03-06
- Inventor: Elena Ranieri , Michele Battaglia , Herr Wolfgang , Loreto Gesualdo
- Applicant: Elena Ranieri , Michele Battaglia , Herr Wolfgang , Loreto Gesualdo
- Applicant Address: IT Bari IT Foggia
- Assignee: Universita' Degli Studi Di Bari,Universita' Degli Studi Di Foggia
- Current Assignee: Universita' Degli Studi Di Bari,Universita' Degli Studi Di Foggia
- Current Assignee Address: IT Bari IT Foggia
- Agency: Medlen & Carroll, LLP
- Priority: ITMI2005A2018 20051021
- International Application: PCT/EP2006/067631 WO 20061020
- International Announcement: WO2007/045691 WO 20070426
- Main IPC: C12N5/09
- IPC: C12N5/09
Abstract:
The present invention relates to a renal carcinoma cell line capable of activating the immune system in an antigen-specific manner. According to a further aspect, the invention also includes derivatives of the cell line that maintain said activation capacity. The invention also comprises a method for targeting and activating immune system cells against cells of clear cell renal carcinoma. Said method comprises the co-incubation of isolated immune system cells (dendritic cells, CD4+, CD8+ lymphocytes etc.) with cells of the RCC BA85#21 line in accordance with the invention in a suitable culture medium, for a time sufficient to obtain antigen specific cells.
Public/Granted literature
- US20090136458A1 Renal Carcinoma Cell Line and Uses thereof Public/Granted day:2009-05-28
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