Invention Grant
US08128935B2 DNA sequence and recombinant production of the grass pollen allergen Phl p 4
有权
DNA序列和重组生产的花粉过敏原Phl p 4
- Patent Title: DNA sequence and recombinant production of the grass pollen allergen Phl p 4
- Patent Title (中): DNA序列和重组生产的花粉过敏原Phl p 4
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Application No.: US10518927Application Date: 2003-06-11
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Publication No.: US08128935B2Publication Date: 2012-03-06
- Inventor: Helmut Fiebig , Andreas Nandy , Roland Suck , Oliver Cromwell , Arnd Petersen , Wolf-Meinhard Becker
- Applicant: Helmut Fiebig , Andreas Nandy , Roland Suck , Oliver Cromwell , Arnd Petersen , Wolf-Meinhard Becker
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: EP02013953 20020625
- International Application: PCT/EP03/06092 WO 20030611
- International Announcement: WO04/000881 WO 20031231
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K39/00 ; A61K39/35 ; A61K39/36 ; A01N37/18 ; C07K1/00 ; C07K14/00 ; C07K17/00
Abstract:
The present invention relates to the provision of the genetic sequence of the major grass pollen allergen Phl p 4. The invention also covers fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilised for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for the in vitro and in vivo diagnosis of pollen allergies.
Public/Granted literature
- US20060177470A1 Dna sequence and recombinant production of the grass pollen allergen phl p4 Public/Granted day:2006-08-10
Information query
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