Invention Grant
- Patent Title: Bisulfite conversion of DNA
- Patent Title (中): 亚硫酸氢盐转化DNA
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Application No.: US11887609Application Date: 2006-03-31
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Publication No.: US08129107B2Publication Date: 2012-03-06
- Inventor: Ina Fuhrmann , Matthias Ballhause
- Applicant: Ina Fuhrmann , Matthias Ballhause
- Applicant Address: DE Berlin
- Assignee: Epigenomics AG
- Current Assignee: Epigenomics AG
- Current Assignee Address: DE Berlin
- Agency: Kriegsman & Kriegsman
- Priority: EP05090090 20050401; EP05090135 20050512
- International Application: PCT/EP2006/003193 WO 20060331
- International Announcement: WO2006/103111 WO 20061005
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; B01L3/00 ; C07H21/00
Abstract:
The present invention relates to an improved method for the bisulfite conversion of DNA. In certain time-temperature ranges the efficacy of the bisulfite conversion is clearly improved. By combination with denaturating solvents, new reaction conditions and new purification methods the efficacy can be further increased The converted DNA can subsequently be analysed by different methods. The present invention facilitates the analysis of cytosine methylation.
Public/Granted literature
- US20100041024A1 Bisulfite Conversion of DNA Public/Granted day:2010-02-18
Information query
