Invention Grant
- Patent Title: Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same
- Patent Title (中): 展现聚集诱发发射的荧光水溶性共轭多烯化合物及其制备和使用方法
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Application No.: US12453892Application Date: 2009-05-26
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Publication No.: US08129111B2Publication Date: 2012-03-06
- Inventor: Benzhong Tang , Yuning Hong , Matthias Haeussler , Hui Tong , Yongqiang Dong , Zhen Li , Changmin Xing
- Applicant: Benzhong Tang , Yuning Hong , Matthias Haeussler , Hui Tong , Yongqiang Dong , Zhen Li , Changmin Xing
- Applicant Address: CN Hong Kong
- Assignee: The Hong Kong University of Science and Technology
- Current Assignee: The Hong Kong University of Science and Technology
- Current Assignee Address: CN Hong Kong
- Agency: The Nath Law Group
- Agent Tanya E. Harkins; Mih Suhn Koh
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/70 ; G01N33/53

Abstract:
The presently described subject matter is directed to water-soluble conjugated polyene compounds that exhibit aggregation induced emission, as well as to water dispersible, fluorescent, polymeric microparticles and/or nanoparticles comprising the water-soluble conjugated polyene compounds. Also provided are methods of making and using the compounds and particles. The described conjugated polyene compounds are useful as bioprobes for the detection biomacromolecules, as well as in the manufacture of sensors.
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