Invention Grant
- Patent Title: Method of screening for inhibitors of glutaminyl cyclase activity
- Patent Title (中): 筛选谷氨酰胺环化酶活性抑制剂的方法
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Application No.: US12497082Application Date: 2009-07-02
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Publication No.: US08129160B2Publication Date: 2012-03-06
- Inventor: Stephan Schilling , Holger Cynis , Jens-Ulrich Rahfeld , Hans-Ulrich Demuth
- Applicant: Stephan Schilling , Holger Cynis , Jens-Ulrich Rahfeld , Hans-Ulrich Demuth
- Applicant Address: DE Halle (Salle)
- Assignee: Probiodrug AG
- Current Assignee: Probiodrug AG
- Current Assignee Address: DE Halle (Salle)
- Agency: SNR Denton US LLP
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N9/10 ; C12N1/20 ; C12N15/00 ; C07H21/04
Abstract:
Novel glutaminyl-peptide cyclotransferase-like proteins (QPCTLs), which are isoenzymes of glutaminyl cyclase (QC, EC 2.3.2.5), and to isolated nucleic acids coding for these isoenzymes, all of which are useful for the discovery of new therapeutic agents, for measuring cyclase activity, and for determining the inhibitory activity of compounds against these glutaminyl cyclase isoenzymes.
Public/Granted literature
- US20100009337A1 NOVEL GENES RELATED TO GLUTAMINYL CYCLASE Public/Granted day:2010-01-14
Information query
