Invention Grant
- Patent Title: Treatment of disease by inducing cell apoptosis
- Patent Title (中): 通过诱导细胞凋亡治疗疾病
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Application No.: US12189526Application Date: 2008-08-11
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Publication No.: US08129349B2Publication Date: 2012-03-06
- Inventor: Mario Chojkier , Martina Buck
- Applicant: Mario Chojkier , Martina Buck
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Medlen & Carroll, LLP
- Main IPC: A61K38/07
- IPC: A61K38/07

Abstract:
The present invention relates generally to the treatment and prevention of diseases characterized by excess cell proliferation and/or activation. In particular, the present invention provides compositions and methods to suppress the activation and/or proliferation of various cells. In some preferred embodiments, the present invention provides compositions and methods to suppress the activation and/or proliferation of mesenchymally derived cells (including, but not limited to hepatic stellate cells), as well as cells with abnormal growth characteristics. In some particularly preferred embodiments, the present invention provides compositions and methods to inhibit or eliminate fibrosis. In alternative preferred embodiments, the present invention provides compositions and methods to induce fibrosis. In still further embodiments, the present invention provides methods and compositions to treat and/or prevent cancer.
Public/Granted literature
- US20100035825A1 Treatment Of Disease By Inducing Cell Apoptosis Public/Granted day:2010-02-11
Information query
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