Invention Grant
US08129371B2 Thienopyrimidine and pyrazolopyrimidine compounds and their use as mTOR kinase and PI3 kinase inhibitors
失效
噻吩并嘧啶和吡唑并嘧啶化合物及其作为mTOR激酶和PI3激酶抑制剂的用途
- Patent Title: Thienopyrimidine and pyrazolopyrimidine compounds and their use as mTOR kinase and PI3 kinase inhibitors
- Patent Title (中): 噻吩并嘧啶和吡唑并嘧啶化合物及其作为mTOR激酶和PI3激酶抑制剂的用途
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Application No.: US12251712Application Date: 2008-10-15
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Publication No.: US08129371B2Publication Date: 2012-03-06
- Inventor: Arie Zask , Joshua Aaron Kaplan , Jeroen Cunera Verheijen , Kevin J. Curran , David James Richard , Semiramis Ayral-Kaloustian
- Applicant: Arie Zask , Joshua Aaron Kaplan , Jeroen Cunera Verheijen , Kevin J. Curran , David James Richard , Semiramis Ayral-Kaloustian
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent David A. Rubin
- Main IPC: C07D265/36
- IPC: C07D265/36 ; C07D265/28 ; A61K31/537 ; A61P37/06 ; A61P35/00 ; C07D487/04 ; C07D495/04
Abstract:
The invention relates to thienopyrimidine and pyrazolopyrimidine compounds of the Formulas (Ia) and (IIa), or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein compositions comprising the compounds, and methods for making and using the compounds.
Public/Granted literature
- US20090098086A1 THIENOPYRIMIDINE AND PYRAZOLOPYRIMIDINE COMPOUNDS AND THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS Public/Granted day:2009-04-16
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