Invention Grant
- Patent Title: Compounds having NPY Y5 receptor antagonistic activity
- Patent Title (中): 具有NPY Y5受体拮抗活性的化合物
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Application No.: US12936693Application Date: 2009-04-20
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Publication No.: US08129372B2Publication Date: 2012-03-06
- Inventor: Masahiro Sakagami
- Applicant: Masahiro Sakagami
- Applicant Address: JP Osaka-shi
- Assignee: Shionogi & Co., Ltd.
- Current Assignee: Shionogi & Co., Ltd.
- Current Assignee Address: JP Osaka-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2008-109778 20080421
- International Application: PCT/JP2009/057856 WO 20090420
- International Announcement: WO2009/131096 WO 20091029
- Main IPC: A61K31/536
- IPC: A61K31/536 ; A61K31/4439 ; A61K31/40 ; A61K31/4174 ; A61K31/415 ; A61K31/4196 ; A61K31/404 ; A61K31/506 ; A61K31/497 ; A61K31/427 ; A61K31/422 ; A61K31/5377 ; A61K31/519 ; A61K31/4985 ; A61K31/444 ; C07D401/10 ; C07D401/14 ; C07D207/335 ; C07D233/64 ; C07D231/12 ; C07D249/08 ; C07D209/14 ; C07D403/10 ; C07D417/10 ; C07D413/10 ; A61P3/04

Abstract:
This invention provides a compound of the formula (I): a pharmaceutically acceptable salt or solvate thereof, wherein R1 is substituted or unsubstituted alkyl or the like, R2 is hydrogen or substituted or unsubstituted alkyl, Ring A is monocyclic or bicyclic aromatic heterocycle, R3 is substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl or substituted or unsubstituted heterocycle, R4 is halogen, cyano, substituted or unsubstituted alkyl, substituted or unsubstituted cycloalkyl or the like, m is an integer between 0 and 2, n is an integer between 0 and 5, R is halogen, oxo, cyano, nitro, substituted or unsubstituted alkyl or the like, and p is an integer between 0 and 2 as novel compounds having NPY Y5 antagonistic activity.
Public/Granted literature
- US20110028468A1 COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY Public/Granted day:2011-02-03
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