Invention Grant
- Patent Title: Crystalline forms of MC4R agonist and process for synthesis
- Patent Title (中): MC4R激动剂的结晶形式和合成方法
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Application No.: US11921824Application Date: 2006-06-23
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Publication No.: US08129413B2Publication Date: 2012-03-06
- Inventor: Ralph Calabria , Yu Cheng , Russell R. Ferlita , Ashkan Kamali , Jerry A. Murry , David Mathre , Andrey V. Peresypkin , Karen Thompson , Jian Wang , Robert M. Wenslow
- Applicant: Ralph Calabria , Yu Cheng , Russell R. Ferlita , Ashkan Kamali , Jerry A. Murry , David Mathre , Andrey V. Peresypkin , Karen Thompson , Jian Wang , Robert M. Wenslow
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Kenrick L. Vidale; John C. Todaro
- International Application: PCT/US2006/024573 WO 20060623
- International Announcement: WO2007/002462 WO 20070104
- Main IPC: A61K31/454
- IPC: A61K31/454 ; C07D401/06
Abstract:
The present invention relates to a process for producing N-{(1S)-1-[2-(1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidin-3-yl]carbonyl}piperidin-4-yl)-5-chlorophenyl]ethyl}acetamide, and novel crystalline salts, hydrates, solvates, and polymorphic forms thereof.
Public/Granted literature
- US20090233967A1 Crystalline forms of mc4r agonist and process for synthesis Public/Granted day:2009-09-17
Information query
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