Kernelized spatial-contextual image classification is disclosed. One embodiment comprises generating a first spatial-contextual model to represent a first image, the first spatial-contextual model having a plurality of interconnected nodes arranged in a first pattern of connections with each node connected to at least one other node, generating a second spatial-contextual model to represent a second image using the first pattern of connections, and estimating the distance between corresponding nodes in the first spatial-contextual model and the second spatial-contextual model based on a relationship with adjacent connected nodes to determine a distance between the first image and the second image.