Disclosed is a sanitary, hygienic toothbrush and holder. The holder carries a plurality of pegs on its front surface. At a distal end of the toothbrush handle is an opening, sized to fit cooperatively over a peg of the holder. At least a portion of the margin of the opening is thinned toward the opening from a surface of the handle, so that, in use, at least a portion of the thinned margin rests cooperatively upon the peg of the holder when the toothbrush is placed by a user in a hanging position.