Invention Grant
US08133896B2 Pyrimidine derivatives which are antagonist of the vitronectin receptor
有权
作为玻连蛋白受体的拮抗剂的嘧啶衍生物
- Patent Title: Pyrimidine derivatives which are antagonist of the vitronectin receptor
- Patent Title (中): 作为玻连蛋白受体的拮抗剂的嘧啶衍生物
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Application No.: US12911691Application Date: 2010-10-25
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Publication No.: US08133896B2Publication Date: 2012-03-13
- Inventor: Jean-Michel Lefrancois , Bertrand Heckmann
- Applicant: Jean-Michel Lefrancois , Bertrand Heckmann
- Applicant Address: BE Mechelen
- Assignee: Galapagos NV
- Current Assignee: Galapagos NV
- Current Assignee Address: BE Mechelen
- Agency: Foley & Lardner LLP
- Agent Stephen E. Reiter
- Priority: FR0405407 20040518
- Main IPC: A61K31/505
- IPC: A61K31/505 ; C07D401/14

Abstract:
A subject of the invention is the compounds of formula (I); in which R1, R2, R3, R4 and R have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.
Public/Granted literature
- US20110039867A1 PYRIMIDINE DERIVATIVES WHICH ARE ANTAGONIST OF THE VITRONECTIN RECEPTOR Public/Granted day:2011-02-17
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