Invention Grant
US08133915B2 Interleukin-1 and tumor necrosis factor-α modulators; syntheses of such modulators and methods of using such modulators
有权
白介素-1和肿瘤坏死因子-α调节剂; 这种调节剂的合成和使用这种调节剂的方法
- Patent Title: Interleukin-1 and tumor necrosis factor-α modulators; syntheses of such modulators and methods of using such modulators
- Patent Title (中): 白介素-1和肿瘤坏死因子-α调节剂; 这种调节剂的合成和使用这种调节剂的方法
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Application No.: US13007573Application Date: 2011-01-14
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Publication No.: US08133915B2Publication Date: 2012-03-13
- Inventor: Michael A. Palladino , Emmanuel A. Theodorakis , Venkat Rami Reddy Macherla , Ta-Hsiang Chao , Young-Ger Suh
- Applicant: Michael A. Palladino , Emmanuel A. Theodorakis , Venkat Rami Reddy Macherla , Ta-Hsiang Chao , Young-Ger Suh
- Applicant Address: US CA San Diego US CA Oakland
- Assignee: Nereus Pharmaceuticals, Inc.,The Regents of the University of California
- Current Assignee: Nereus Pharmaceuticals, Inc.,The Regents of the University of California
- Current Assignee Address: US CA San Diego US CA Oakland
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61K31/165
- IPC: A61K31/165
Abstract:
Described herein are chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. Also described are methods of synthesizing natural products and novel, structurally-related chemical compounds. More particularly, disclosed are new analogs of and processes for the preparation of compounds and pharmaceutical compositions thereof useful in the treatment of, for example, inflammation, cancer, multiple myeloma, cachexia, cardiovascular disease, anti-infectious, diabetes, otitis media, sinusitis and transplant rejection.
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