A method for combined static and dynamic compilation of program code to remove delinquent loads can include statically compiling source code into executable code with instrumented sections each being suspected of including a delinquent load, and also into a separate intermediate language representation with annotated portions each corresponding to one of the instrumented sections. The method also can include executing the instrumented sections repeatedly and monitoring cache misses for each execution. Finally, the method can include dynamically recompiling selected ones of the instrumented sections using corresponding ones of the annotated portions of the separate intermediate language representation only after a threshold number of executions of the selected ones of the instrumented sections, each recompilation include a pre-fetch directive at a pre-fetch distances tuned to avoid the delinquent load.