An organic-inorganic lighting device and a method for fabricating the same is disclosed. Firstly, a conductive substrate is provided, and an inorganic conducting film layer and a seed layer are formed in turn on the conductive substrate. Next, an array of micro and nano zinc oxide wire is formed on the seed layer by using properties of the seed layer. Finally, an electrode layer is formed on the array of micro and nano zinc oxide wire. The invention solves the problem of low mobility of electrons in inorganic materials.