Provided are a liquid ejection cartridge and a liquid ejection device each having a simple structure capable of surely mixing a plurality of liquids. An example of the liquid ejection cartridge includes a liquid ejection portion (12) for ejecting a liquid; a first liquid storage portion (3) which is separated from the liquid ejection portion (12) through a film (10); a second liquid storage portion (4) which is separated from the first liquid storage portion (3) through a film (9). Further, the liquid ejection cartridge further includes a first penetrating member (8) for penetrating the film (10) which separates the liquid ejection portion (12) and the first liquid storage portion (3); and a second penetrating member (7) for penetrating the film (9) which separates the first liquid storage portion (3) and the second liquid storage portion (4).