Modular pillboxes that include at least one one-way passage through which pills, materials or other articles can be pushed through and into and underlying interior compartment of the modular pillboxes. The modular pillboxes include coupling structure by which the modular pillbox can be coupled to a loading tray and/or additional modular pillboxes. The modular pillboxes include lids that can be opened to access pills, materials or other articles that are loaded therein through the one-way passages.