Invention Grant
US08147833B2 Prevention and treatment of synucleinopathic and amyloidogenic disease
有权
预防和治疗突触核蛋白病和淀粉样变性疾病
- Patent Title: Prevention and treatment of synucleinopathic and amyloidogenic disease
- Patent Title (中): 预防和治疗突触核蛋白病和淀粉样变性疾病
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Application No.: US12528439Application Date: 2008-02-22
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Publication No.: US08147833B2Publication Date: 2012-04-03
- Inventor: Dale B. Schenk , Eliezer Masliah , Manuel J. Buttini , Tamie J. Chilcote , Edward Rockenstein , Kate Dora Games
- Applicant: Dale B. Schenk , Eliezer Masliah , Manuel J. Buttini , Tamie J. Chilcote , Edward Rockenstein , Kate Dora Games
- Applicant Address: IE Dublin US CA Oakland
- Assignee: Neotope Biosciences Limited,The Regents of the University of California
- Current Assignee: Neotope Biosciences Limited,The Regents of the University of California
- Current Assignee Address: IE Dublin US CA Oakland
- Agency: Alston & Bird LLP
- International Application: PCT/US2008/002392 WO 20080222
- International Announcement: WO2008/103472 WO 20080828
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The invention provides improved agents and methods for treatment of diseases associated with synucleinopathic diseases, including Lewy bodies of alpha-synuclein in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the Lewy body. The methods are particularly useful for prophylactic and therapeutic treatment of Parkinson's disease.
Public/Granted literature
- US20100086545A1 Prevention and Treatment of Synucleinopathic and Amyloidogenic Disease Public/Granted day:2010-04-08
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