Invention Grant
US08147845B2 Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions
有权
来自混合细胞组合物的ras介导的肿瘤细胞的呼肠孤病毒清除
- Patent Title: Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions
- Patent Title (中): 来自混合细胞组合物的ras介导的肿瘤细胞的呼肠孤病毒清除
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Application No.: US12726002Application Date: 2010-03-17
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Publication No.: US08147845B2Publication Date: 2012-04-03
- Inventor: Donald Morris , Bradley G. Thompson , Matthew C. Coffey
- Applicant: Donald Morris , Bradley G. Thompson , Matthew C. Coffey
- Applicant Address: US CA Calgary, Alberta
- Assignee: Oncolytics Biotech Inc.
- Current Assignee: Oncolytics Biotech Inc.
- Current Assignee Address: US CA Calgary, Alberta
- Agency: McKeon Meunier Carlin & Curfman, LLC
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/38 ; A61K39/395 ; G01N1/00 ; G01N33/48 ; C12Q1/00
Abstract:
Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autographs back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.
Public/Granted literature
- US20100248205A1 Reovirus Clearance of Ras-Mediated Neoplastic Cells from Mixed Cellular Compositions Public/Granted day:2010-09-30
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