Invention Grant
- Patent Title: Ligation amplification of nucleic acid sequences
- Patent Title (中): 核酸序列的连接扩增
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Application No.: US07996771Application Date: 1992-12-24
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Publication No.: US08148065B1Publication Date: 2012-04-03
- Inventor: R. Bruce Wallace
- Applicant: R. Bruce Wallace
- Applicant Address: US CA Duarte
- Assignee: City of Hope
- Current Assignee: City of Hope
- Current Assignee Address: US CA Duarte
- Agency: Rothwell, Figg, Ernst & Manbeck P.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
A method is described for the identification of point mutations by a template-dependent ligation procedure. Also described is a template-dependent ligase chain reaction procedure for the amplification and detection of nucleic acid sequences.
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