Invention Grant
- Patent Title: Methods to predict and prevent resistance to taxoid compounds
- Patent Title (中): 预防和预防紫杉类化合物抗性的方法
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Application No.: US12085125Application Date: 2006-11-17
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Publication No.: US08148086B2Publication Date: 2012-04-03
- Inventor: Bruce R. Zetter , Sabarni K. Chatterjee
- Applicant: Bruce R. Zetter , Sabarni K. Chatterjee
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporatioin
- Current Assignee: Children's Medical Center Corporatioin
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2006/044819 WO 20061117
- International Announcement: WO2007/061922 WO 20070531
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/574
Abstract:
Embodiments of the invention are directed to methods for predicting the resistance of cancer to members of the taxoid family by measuring the levels of prohibitin. Methods for treating cancer and taxoid family member resistant cancers using inhibitors of prohibitin, as well as therapeutic complexes that target prohibitin are also provided.
Public/Granted literature
- US20090312405A1 Methods to Predict and Prevent Resistance to Taxoid Compounds Public/Granted day:2009-12-17
Information query
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