Invention Grant
US08148111B2 Cell culture carrier comprising poly(meth)acrylic (salt) particle and artificial polypeptide 有权
包含聚(甲基)丙烯酸(盐)颗粒和人造多肽的细胞培养载体

Cell culture carrier comprising poly(meth)acrylic (salt) particle and artificial polypeptide
Abstract:
A carrier for cell culture is provided which improves the cell proliferativity in serum-free culture and which is free from risk from infection factor contamination. The gist of the features of the present invention is to be formed of a crosslinked poly(meth)acrylic acid (salt) particle (A) and an artificial polypeptide (P) having at least one cell-adhesive minimal amino acid sequence (X) in one molecule and to have a water retention value of from 2 to 50 g/g. The (A) is preferably a particle produced by reversed phase suspension polymerization of an aqueous monomer solution containing (meth)acrylic acid and/or an alkali metal salt of (meth)acrylic acid. The (P) preferably has at least one auxiliary amino acid sequence (Y) in one molecule of the (P). The (X) is preferably an Arg Gly Asp sequence.
Public/Granted literature
Information query
Patent Agency Ranking
0/0