Invention Grant
US08148111B2 Cell culture carrier comprising poly(meth)acrylic (salt) particle and artificial polypeptide
有权
包含聚(甲基)丙烯酸(盐)颗粒和人造多肽的细胞培养载体
- Patent Title: Cell culture carrier comprising poly(meth)acrylic (salt) particle and artificial polypeptide
- Patent Title (中): 包含聚(甲基)丙烯酸(盐)颗粒和人造多肽的细胞培养载体
-
Application No.: US12293147Application Date: 2007-03-13
-
Publication No.: US08148111B2Publication Date: 2012-04-03
- Inventor: Masato Kurokawa , Kazuhiro Takahashi
- Applicant: Masato Kurokawa , Kazuhiro Takahashi
- Applicant Address: JP Kyoto-shi
- Assignee: Sanyo Chemical Industries, Ltd.
- Current Assignee: Sanyo Chemical Industries, Ltd.
- Current Assignee Address: JP Kyoto-shi
- Agency: Westerman, Hattori, Daniels & Adrian, LLP
- Priority: JP2006-074009 20060317
- International Application: PCT/JP2007/000217 WO 20070313
- International Announcement: WO2007/108205 WO 20070927
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N11/08 ; C12N5/00 ; C12N5/07

Abstract:
A carrier for cell culture is provided which improves the cell proliferativity in serum-free culture and which is free from risk from infection factor contamination. The gist of the features of the present invention is to be formed of a crosslinked poly(meth)acrylic acid (salt) particle (A) and an artificial polypeptide (P) having at least one cell-adhesive minimal amino acid sequence (X) in one molecule and to have a water retention value of from 2 to 50 g/g. The (A) is preferably a particle produced by reversed phase suspension polymerization of an aqueous monomer solution containing (meth)acrylic acid and/or an alkali metal salt of (meth)acrylic acid. The (P) preferably has at least one auxiliary amino acid sequence (Y) in one molecule of the (P). The (X) is preferably an Arg Gly Asp sequence.
Public/Granted literature
- US20090136912A1 CARRIER FOR CELL CULTURE Public/Granted day:2009-05-28
Information query