Invention Grant
US08148384B2 Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics
有权
取代的噻吩并[3,2-d]嘧啶PIM激酶抑制剂作为癌症化学治疗剂
- Patent Title: Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics
- Patent Title (中): 取代的噻吩并[3,2-d]嘧啶PIM激酶抑制剂作为癌症化学治疗剂
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Application No.: US11951546Application Date: 2007-12-06
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Publication No.: US08148384B2Publication Date: 2012-04-03
- Inventor: Thomas D. Penning , Lisa A. Hasvold , Laura A. Hexamer , Vincent L. Giranda , Nan-horng Lin , Zhi-Fu Tao , Le Wang
- Applicant: Thomas D. Penning , Lisa A. Hasvold , Laura A. Hexamer , Vincent L. Giranda , Nan-horng Lin , Zhi-Fu Tao , Le Wang
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Susan L. Steele
- Main IPC: C07D495/04
- IPC: C07D495/04 ; A61K31/519 ; A61P35/00 ; C07D495/14
![Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics](/abs-image/US/2012/04/03/US08148384B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of formula I wherein A1, A2, and A3 are as defined herein are inhibitors of PIM kinase. The compounds of formula I are useful for the treatment of diseases such as cancer.
Public/Granted literature
- US20080161559A1 PIM KINASE INHIBITORS AS CANCER CHEMOTHERAPEUTICS Public/Granted day:2008-07-03
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