Invention Grant
US08148385B2 Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists
有权
取代的[1,2,3]三唑并[4,5-d]嘧啶衍生物作为ADP P2Y12受体拮抗剂
![Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists](/docs/US/2012-04-03/US08148385B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists
- Patent Title (中): 取代的[1,2,3]三唑并[4,5-d]嘧啶衍生物作为ADP P2Y12受体拮抗剂
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Application No.: US11980907Application Date: 2007-10-31
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Publication No.: US08148385B2Publication Date: 2012-04-03
- Inventor: Han-Cheng Zhang , Bruce E. Maryanoff , Hong Ye , Cailin Chen
- Applicant: Han-Cheng Zhang , Bruce E. Maryanoff , Hong Ye , Cailin Chen
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE
- Agent Yuriy P. Stercho
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P7/02 ; A61P9/10 ; A61P37/06 ; A61P25/06
![Substituted [1,2,3] triazolo[4,5-d]pyrimidine derivatives as ADP P2Y12 receptor antagonists](/abs-image/US/2012/04/03/US08148385B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to novel bicyclic triazolopyrimidine compounds of Formula (I) or a form thereof: wherein X1, X2, R1, R2, R3 and R4 are as defined herein, and their methods of preparation and use as ADP inhibitors.
Public/Granted literature
- US20080312257A1 Triazolopyrimidine derivatives as ADP P2Y12 receptor antagonists Public/Granted day:2008-12-18
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