Invention Grant
- Patent Title: Thiophene derivatives as agonists of S1P1/EDG1
- Patent Title (中): 噻吩衍生物作为S1P1 / EDG1的激动剂
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Application No.: US12747280Application Date: 2008-12-09
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Publication No.: US08148410B2Publication Date: 2012-04-03
- Inventor: Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
- Applicant: Martin Bolli , Cyrille Lescop , Boris Mathys , Claus Mueller , Oliver Nayler , Beat Steiner
- Applicant Address: CH Allschwil
- Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee: Actelion Pharmaceuticals Ltd.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates LLC
- Priority: WOPCT/IB2007/054991 20071210
- International Application: PCT/IB2008/055156 WO 20081209
- International Announcement: WO2009/074950 WO 20090618
- Main IPC: A61K31/381
- IPC: A61K31/381 ; A61K31/4245 ; A61K31/41 ; C07D271/06 ; C07D271/10 ; C07D285/16 ; C07D409/04
Abstract:
The invention relates to novel thiophene derivatives (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. Formula (I).
Public/Granted literature
- US20100261702A1 THIOPHENE DERIVATIVES AS AGONISTS OF S1P1/EDG1 Public/Granted day:2010-10-14
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