Invention Grant
US08148412B2 Heteroaromatic glucokinase activators 有权
杂芳香葡萄糖激酶激活剂

Heteroaromatic glucokinase activators
Abstract:
The present invention describes 2,3-di-substituted N-heteroaromatic propionamides, of Formula (I) wherein the substitution at the 3-position is an optionally substituted phenyl ring and the substitution at the 2-position is an alkyl or cycloalkyl group; pharmaceutical compositions comprising the same; and, methods of using the same. The propionamides are glucokinase activators for the treatment of type II diabetes.
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