Invention Grant
US08148413B2 N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes
有权
N-杂芳基吲哚羧酰胺及其类似物，用作糖尿病治疗中的葡糖激酶活化剂
- Patent Title: N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes
- Patent Title (中): N-杂芳基吲哚羧酰胺及其类似物，用作糖尿病治疗中的葡糖激酶活化剂
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Application No.: US12895761Application Date: 2010-09-30
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Publication No.: US08148413B2Publication Date: 2012-04-03
- Inventor: Jesper Lau , Per Vedsø , János Tibor Kodra , Anthony Murray , Lone Jeppesen , Michael Ankersen , Govindan Subramanian , Adnan M. M. Mjalli , Robert Carl Andrews , Dharma Rao Polisetti , Daniel Peter Christen
- Applicant: Jesper Lau , Per Vedsø , János Tibor Kodra , Anthony Murray , Lone Jeppesen , Michael Ankersen , Govindan Subramanian , Adnan M. M. Mjalli , Robert Carl Andrews , Dharma Rao Polisetti , Daniel Peter Christen
- Applicant Address: US NC High Point
- Assignee: TransTech Pharma, Inc.
- Current Assignee: TransTech Pharma, Inc.
- Current Assignee Address: US NC High Point
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: EP03388079 20031124
- Main IPC: A61K31/427
- IPC: A61K31/427 ; C07D417/12
Abstract:
This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherein A and B are further defined in the application.
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