Invention Grant
US08148431B2 Osteogenesis promoter containing β-cryptoxanthin as the active ingredient 有权
含骨质疏松促进剂含有黄曲霉毒素作为活性成分

  • Patent Title: Osteogenesis promoter containing β-cryptoxanthin as the active ingredient
  • Patent Title (中): 含骨质疏松促进剂含有黄曲霉毒素作为活性成分
  • Application No.: US10532775
    Application Date: 2003-10-03
  • Publication No.: US08148431B2
    Publication Date: 2012-04-03
  • Inventor: Masayoshi Yamaguchi
  • Applicant: Masayoshi Yamaguchi
  • Applicant Address: US IA Des Moines
  • Assignee: Kemin Health, L.C.
  • Current Assignee: Kemin Health, L.C.
  • Current Assignee Address: US IA Des Moines
  • Agent Kent A. Herink; Emily E. Harris
  • Priority: JP2002-311930 20021025
  • International Application: PCT/JP03/13561 WO 20031003
  • International Announcement: WO2004/037236 WO 20040506
  • Main IPC: A61K31/07
  • IPC: A61K31/07
Osteogenesis promoter containing β-cryptoxanthin as the active ingredient
Abstract:
It is intended to provide an osteogenesis promoter having a remarkable effect of positively promoting osteogenesis and thus preventing/treating bone diseases; a preventive/a remedy for bone diseases such as osteoporosis having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect; and a method of screening an active ingredient for preventing/treating bone diseases by using a compound having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect as a lead compound. It is confirmed that beta-cryptoxanthin, which occurs in a large amount in peel and sarcocarp of satsuma orange, has an osteogenesis-promoting effect and a therapeutic effect on bone disease. Thus, beta-cryptoxanthin or its composition is used as an osteogenesis promoter, a preventive/a remedy for bone diseases, a functional food or a food material for preventing/treating bone diseases and a feed composition.
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