Invention Grant
US08148431B2 Osteogenesis promoter containing β-cryptoxanthin as the active ingredient
有权
含骨质疏松促进剂含有黄曲霉毒素作为活性成分
- Patent Title: Osteogenesis promoter containing β-cryptoxanthin as the active ingredient
- Patent Title (中): 含骨质疏松促进剂含有黄曲霉毒素作为活性成分
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Application No.: US10532775Application Date: 2003-10-03
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Publication No.: US08148431B2Publication Date: 2012-04-03
- Inventor: Masayoshi Yamaguchi
- Applicant: Masayoshi Yamaguchi
- Applicant Address: US IA Des Moines
- Assignee: Kemin Health, L.C.
- Current Assignee: Kemin Health, L.C.
- Current Assignee Address: US IA Des Moines
- Agent Kent A. Herink; Emily E. Harris
- Priority: JP2002-311930 20021025
- International Application: PCT/JP03/13561 WO 20031003
- International Announcement: WO2004/037236 WO 20040506
- Main IPC: A61K31/07
- IPC: A61K31/07

Abstract:
It is intended to provide an osteogenesis promoter having a remarkable effect of positively promoting osteogenesis and thus preventing/treating bone diseases; a preventive/a remedy for bone diseases such as osteoporosis having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect; and a method of screening an active ingredient for preventing/treating bone diseases by using a compound having both of an osteogenesis-promoting effect and a bone resorption-inhibiting effect as a lead compound. It is confirmed that beta-cryptoxanthin, which occurs in a large amount in peel and sarcocarp of satsuma orange, has an osteogenesis-promoting effect and a therapeutic effect on bone disease. Thus, beta-cryptoxanthin or its composition is used as an osteogenesis promoter, a preventive/a remedy for bone diseases, a functional food or a food material for preventing/treating bone diseases and a feed composition.
Public/Granted literature
- US20060106115A1 Osteogenesis promoter containing beta-cryptoxanthin as the active ingredient Public/Granted day:2006-05-18
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