Invention Grant
- Patent Title: Aminoglycoside antibiotics
- Patent Title (中): 氨基糖苷类抗生素
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Application No.: US12227861Application Date: 2007-06-01
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Publication No.: US08148504B2Publication Date: 2012-04-03
- Inventor: Yoshihiko Kobayashi , Yoshihisa Akiyama , Takeshi Murakami , Nobuto Minowa , Masaki Tsushima , Yukiko Hiraiwa , Shoichi Murakami , Mitsuhiro Abe , Kazushige Sasaki , Shigeru Hoshiko , Toshiaki Miyake , Yoshiaki Takahashi , Daishiro Ikeda
- Applicant: Yoshihiko Kobayashi , Yoshihisa Akiyama , Takeshi Murakami , Nobuto Minowa , Masaki Tsushima , Yukiko Hiraiwa , Shoichi Murakami , Mitsuhiro Abe , Kazushige Sasaki , Shigeru Hoshiko , Toshiaki Miyake , Yoshiaki Takahashi , Daishiro Ikeda
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Meiji Seika Pharma Co., Ltd.,Microbial Chemistry Research Foundation
- Current Assignee: Meiji Seika Pharma Co., Ltd.,Microbial Chemistry Research Foundation
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2006-155062 20060602
- International Application: PCT/JP2007/061209 WO 20070601
- International Announcement: WO2007/142150 WO 20071213
- Main IPC: C07H13/02
- IPC: C07H13/02

Abstract:
This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly MRSA, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (Ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them.
Public/Granted literature
- US20090186841A1 Novel aminoglycoside antibiotics Public/Granted day:2009-07-23
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