Invention Grant
US08148509B2 Transgene delivering retrovirus targeting collagen exposed at site of tissue injury
有权
转运基因导致组织损伤部位暴露的靶向胶原蛋白的逆转录病毒
- Patent Title: Transgene delivering retrovirus targeting collagen exposed at site of tissue injury
- Patent Title (中): 转运基因导致组织损伤部位暴露的靶向胶原蛋白的逆转录病毒
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Application No.: US12879511Application Date: 2010-09-10
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Publication No.: US08148509B2Publication Date: 2012-04-03
- Inventor: Frederick L. Hall , Erlinda M. Gordon
- Applicant: Frederick L. Hall , Erlinda M. Gordon
- Applicant Address: US CA Los Angeles
- Assignee: University of Southern California
- Current Assignee: University of Southern California
- Current Assignee Address: US CA Los Angeles
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K48/00
Abstract:
A viral or non-viral vector particle having a modified viral surface protein wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds to an extracellular matrix component. Such vector particles are useful in delivering genes encoding therapeutic agents to cells located at the site of an exposed extracellular matrix component.
Public/Granted literature
- US20110065179A1 TRANSGENE DELIVERING RETROVIRUS TARGETING COLLAGEN EXPOSED AT SITE OF TISSUE INJURY Public/Granted day:2011-03-17
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