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US08148520B2 Process for the preparation of beta-lactam antibiotic meropenem trihydrate 有权
β-内酰胺抗生素美罗培南三水合物的制备方法

Process for the preparation of beta-lactam antibiotic meropenem trihydrate
Abstract:
A process for preparing purified Meropenem trihydrate that involves the dissolution of Meropenem in water in presence of base, adjusting the pH to 4.0-7.0, and adding solvent to yield Meropenem trihydrate.
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